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Producing a strong positive cerebral high that can make users feel very energetic, the strain also carries some mellow body effects from its Indica lineage. Although numbing and soothing, Blue Crack's body high rarely results in couch-lock. Users often report that their creative juices are flowing more freely. The strain also carries traditional negative effects such as dry eyes and mouth, dizziness, and occasional paranoia.
 
Blue Crack, a good daytime strain, is most often used by patients seeking relief from chronic aches and pains. To a lesser degree, Blue Crack is prescribed for anxiety, stress, and depression related disorders due to the high-energy and upbeat nature of the high. A smaller subset of individuals use it to ease migraines.